KPV Peptide - 10mg

Peptide Profile

• Peptide Name: KPV (Lys-Pro-Val), α-MSH(11–13)

• CAS Number (free acid): 67727-97-3 (variant Ac-KPV-NH 2 : CAS 112965-21-6)

• Molecular Formula (free acid): C 16 H 30 N 4 O 4

• Molecular Weight (free acid): 342.43 g/mol

• Main Function: Potent anti-inflammatory and immune-modulating tripeptide

• Mechanism of Action: Suppresses pro-inflammatory cytokines (TNF-α, IL-1β, IL-6), reduces immune cell infiltration, enhances tissue repair, and supports antimicrobial defense. Uptake is mediated via PepT1 transporters, ensuring strong effects in gut and barrier tissues.

The Amino Acid Advantage

• Lysine (K): Essential for tissue repair, antibody and enzyme production, and immune balance. In KPV, Lysine plays a key role in modulating inflammatory activity.

• Proline (P): A structural amino acid that stabilizes proteins. Proline ensures KPV maintains the right conformation to interact effectively with cellular targets.

• Valine (V): A branched-chain amino acid important for protein synthesis and energy metabolism. Valine supports cellular uptake of KPV and amplifies its biological effects.

Key Features & Benefits

• Reduces inflammation by silencing cytokine activity

• Balances immune response and reduces autoimmune triggers

• Supports skin health and barrier protection (psoriasis, eczema, dermatitis)

• Accelerates wound healing and tissue regeneration

• Relieves pain linked to inflammatory processes

• Protects gut lining and promotes intestinal health in IBD contexts

• Provides antimicrobial defense against certain pathogens

• Enhances recovery and overall vitality for anti-aging support

Best For

• Athletes recovering from intense training or injury

• Biohackers and longevity seekers focused on anti-aging and systemic wellness

• Individuals managing gut issues or skin conditions

• Anyone looking to calm chronic inflammation and improve daily resilience

Recommended Dosage & Administration

• Typical Daily Dose: 500 mcg (10 units) once per day

• Cycle Duration: 4–8 weeks depending on individual goals

• Administration: Subcutaneous injection into the abdomen or front thigh. Rotate injection sites for comfort. After injecting, wait ~10 seconds before removing the needle.

Pen Conversion (10 mg / 200 units)

• 1 unit = 50 mcg

• 4 units = 200 mcg

• 5 units = 250 mcg

• 10 units = 500 mcg

Supply Guide: A 10 mg pen contains 200 units (50 mcg each). At 500 mcg/day (10 units), one pen provides ~20 days of use.

What is KPV?

KPV is a synthetic tripeptide fragment of α-MSH designed through advanced research into melanocortins. Unlike the full hormone, KPV does not affect pigmentation but retains its anti-inflammatory , antimicrobial , and healing benefits. Its small size ensures efficient cellular uptake, allowing it to regulate NF-κB and MAPK pathways, suppress cytokines, and enhance natural repair mechanisms.

Benefits

• Faster recovery from injury and training

• Joint and tendon comfort

• Stronger gut barrier and smoother digestion

• Clearer, healthier skin with barrier support

• Reduced pain and discomfort from inflammation

• Anti-aging through systemic inflammation control

• Improved wound closure and less scarring

• Immune system balance for greater resilience

• Antimicrobial protection for better defense

Clinical Research

Preclinical studies confirm KPV’s potent action in colitis, skin inflammation, and wound healing models . In animal trials, KPV reduced cytokine release, suppressed NF-κB and MAPK activation, and protected intestinal tissue. Advanced formulations such as hydrogels and nanoparticles show strong delivery potential, underscoring KPV’s growing scientific relevance.

Possible Side Effects

• Brief stomach discomfort or short-term diarrhea (rare, mild)

• Minor redness or irritation at the injection site

Conclusion

KPV Peptide offers a powerful combination of anti-inflammatory, immune-modulating, and regenerative properties in one compact tripeptide. By protecting skin, gut, and connective tissues while accelerating recovery, it supports both performance and long-term wellness.

FAQs

What is KPV?

KPV is a synthetic tripeptide (Lys-Pro-Val), the C-terminal fragment of α-MSH, with potent anti-inflammatory and healing properties.

What are the main benefits?

Stronger gut and skin health, reduced inflammation, faster recovery, pain relief, wound healing, and overall wellness support.

Who can use KPV?

Athletes, biohackers, and individuals managing skin or gut conditions, or anyone looking for anti-aging and recovery support.

How is it administered?

By subcutaneous injection, usually 500 mcg (10 units) once daily.

Are there side effects?

KPV is generally well tolerated, with only rare, mild effects such as temporary GI upset or injection-site irritation.

Is KPV safe?

In practical use scenarios it shows a strong tolerance profile with minimal side effects when used correctly.

Take control of inflammation, accelerate recovery, and unlock peak vitality. Order Nordic Peptides KPV 10mg today and experience the power of pharmaceutical-grade purity and performance.