Výzkum tělesného složení a metabolismu.
Sekce GLP-1 a vše kolem ní: semaglutid, tirzepatid a retatrutid v předplněných perech, spolu s tesamorelinem, AOD9604, tesofensinem a metabolickými směsmi. Jde o nejdůkladněji zkoumanou skupinu v tomto katalogu a naše výzkumné oddělení se zabývá studiemi za jednotlivými sloučeninami, nikoli shrnutím marketingu.
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DEAL −15%Než objednáte
GLP-1Tirzepatide: what SURMOUNT-1 and SURMOUNT-2 actually showed
Two 72-week placebo-controlled trials, 3,477 participants between them — one in obesity without diabetes, one in obesity with type 2 diabetes. The published weight-loss figures, dose by dose, and where the data stop.
PerformanceExercise mimetics: what AICAR, SLU-PP-332 and 5-Amino-1MQ have actually done, and in what species
One of these three has been given to 3,080 humans — and the trial was stopped for futility. The other two have never been given to a human at all. All three are sold on the same phrase, and the phrase comes from one mouse treadmill experiment in 2008.
MetabolicTesofensine: a phase 2 result that never became a phase 3 paper
The 2008 Lancet trial is real, and the numbers in it are large. What followed is the part nobody quotes — an Expression of Concern from the journal, no published phase 3 anywhere in the indexed literature, and no approval in the EU or the US.