Kroppssammansättning och metabol forskning.
GLP-1-hyllan och allt runt omkring den: semaglutid, tirzepatid och retatrutid i förfyllda pennor, tillsammans med tesamorelin, AOD9604, tesofensin och de metabola blandningarna. Det är den mest studerade gruppen i denna katalog, och vår forskningsavdelning täcker studierna bakom varje förening snarare än att sammanfatta marknadsföringen.
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DEAL −15%Innan du beställer
GLP-1Tirzepatide: what SURMOUNT-1 and SURMOUNT-2 actually showed
Two 72-week placebo-controlled trials, 3,477 participants between them — one in obesity without diabetes, one in obesity with type 2 diabetes. The published weight-loss figures, dose by dose, and where the data stop.
PerformanceExercise mimetics: what AICAR, SLU-PP-332 and 5-Amino-1MQ have actually done, and in what species
One of these three has been given to 3,080 humans — and the trial was stopped for futility. The other two have never been given to a human at all. All three are sold on the same phrase, and the phrase comes from one mouse treadmill experiment in 2008.
MetabolicTesofensine: a phase 2 result that never became a phase 3 paper
The 2008 Lancet trial is real, and the numbers in it are large. What followed is the part nobody quotes — an Expression of Concern from the journal, no published phase 3 anywhere in the indexed literature, and no approval in the EU or the US.